Instruction for use: Fastum gel

Active substance Ketoprofen

ATX code M02AA10 Ketoprofen

Pharmacological group

NSAIDs - Propionic acid derivatives

Nosological classification (ICD-10)

G54.1 Disorders of lumbosacral plexus

Sciatica, Neurology radicular origin, spine Pathology, Sciatica lumbosacral, radiculoneuritis

I80 Phlebitis and thrombophlebitis

Diseases of peripheral vessels, Inflammation of superficial veins, Inflammatory diseases of veins, Deep venous thrombophlebitis, The disease of veins, Disease of the veins of the lower extremities, Diseases of peripheral vessels, Migrating phlebitis, Insufficiency of veins of lower extremities, Exacerbation of chronic thrombophlebitis, Acute thrombophlebitis,Acute thrombophlebitis of superficial veins, Periphlebitis, Periflebit surface, Superficial inflammation of veins, Surface thrombophlebitis, Surface phlebitis, Thrombophlebitis, Deep vein thrombophlebitis, Thrombophlebitis superficial, Phlebitis, Phlebitis of deep veins, Phlebitis of superficial veins, Phlebopathy, Chronic thrombophlebitis, Endophlebitis

I88 Nonspecific lymphadenitis

Lymphadenitis, Lymphadenitis of unspecific etiology, Superficial lymphadenitis

I89.1 Lymphangitis

Lymphangitis, Lymphagitis, Lymphangitis acute

M06.9 Other specified rheumatoid arthritis

Rheumatoid arthritis,Pain syndrome in rheumatic diseases, Pain in rheumatoid arthritis, Inflammation in rheumatoid arthritis, Degenerative forms of rheumatoid arthritis, Children's rheumatoid arthritis, Exacerbation of rheumatoid arthritis, Acute articular rheumatism, Rheumatic arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatic polyarthritis, Rheumatoid arthritis, Rheumatoid arthritis of active course, Rheumatoid arthritis, Rheumatoid polyarthritis, Acute rheumatoid arthritis, Acute rheumatism

M10 Gout

Exacerbation of gout, Acute articular attack with gout, Acute gouty attack, Gouty attack, Recurrent gout attacks, Chronic gout

M15-M19 Osteoarthritis

M45 Ankylosing spondylitis

Ankylosing spondylarthrosis, Marie-Strumpel disease, Ankylosing spondylitis, Pain syndrome in acute inflammatory diseases of the musculoskeletal system, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Bechterew's disease, Ankylosing spondylitis, Diseases of the spinal column, Rheumatic spondylitis, Bechterew-Marie-Strumpel disease

M54 Dorsalgia

Pain in the back area, Pain in the spine, Back pain, Pain in different parts of the spine, Backache, Painful pain syndrome in the spine, Pain in the musculoskeletal system

M54.3 Sciatica

Ishialgia, Neuralgia of the sciatic nerve, Sciatic neuritis

M54.4 Lumbago with sciatica

Pain in the lumbosacral spine, Lumbago, Sciatica, Lumbar syndrome

M65 Synovitis and tendosynovitis

Acute tenosynovitis, Tendovaginitis (tenovaginitis), Tendosinovit (tenosynovitis), Tendovaginitis, Osteoarthritis in musculo-articular diseases, Inflammatory disease of soft tissues, Nonspecific tenosynovitis, Tendosinovit

M71 Other bursopathies

Bursitis, Bursopathy, Diseases of soft tissues, Osteoarthritis in musculo-articular diseases, Inflammatory disease of soft tissues, Subacute bursitis

M71.9 Bursopathy, unspecified

Bursites, Alberta disease, Acute bursitis

M77.9 Other unspecified

Capsule, Periarthritis, Tendonitis, Tendopathy, Periarthropathy

M79.0 Other unspecified rheumatism

Degenerative rheumatic disease, Degenerative and rheumatic diseases of the tendons, Degenerative rheumatic diseases, Localized forms of rheumatism of soft tissues, Rheumatism, Rheumatism with a pronounced allergic component, Rheumatism of the articular and extraarticular, Rheumatic attack, Rheumatic complaints, Rheumatic diseases, Rheumatic disease of the spine, Relapses of rheumatism, Articular and extra-articular rheumatism, Articular and muscular rheumatism, Articular rheumatism, Articular syndrome with rheumatism, Chronic rheumatic pain, Chronic articular rheumatism, Rheumatoid diseases, Rheumatic diseases of the intervertebral disc

M79.1 Myalgia

Myofascial pain syndromes ,Pain syndrome in musculo-articular diseases, Pain syndrome in chronic inflammatory diseases of the musculoskeletal system, Pain in the muscles, Tenderness of muscles, Muscular soreness in severe physical exertion, Painful conditions of the musculoskeletal system, Pain in the musculoskeletal system, Pain in the muscles, Pain at rest, Muscle aches, Muscle pain, Musculoskeletal pain, Myalgia, Muscle pain, Muscle pain at rest, Muscle pain, Muscular pain of non-rheumatic origin, Muscle pain of rheumatic origin, Acute muscle pain, Rheumatic pain, Rheumatic pains, Myofascial syndrome, Fibromyalgia

M93.9 Osteochondropathy, unspecified

Keller's disease

T08-T14 Injuries to unspecified part of trunk, limb or body region

T14.3 Dislocation, sprain and damage to the capsular-ligamentous apparatus of the joint of the unspecified area of the body

Painful stretching of muscles, Pain and inflammation in tension, Dislocation of dislocation, Degenerative changes in the ligamentous apparatus, Edema due to sprains and bruises, Edema after interventions for sprains, Damage and rupture of ligaments, The musculoskeletal system is damaged, Damage to ligaments, Damage to the joints, Ligament ruptures, Tendon tendons,Ruptures of the tendons of muscles,Stretching, Crick, Stretching of the muscle, Sprain, Tension of the tendons, Extensions,Stretch muscles, Sprains, Tension of the tendons, Injury of the musculoskeletal system, Injuries to the joints, Injuries of capsule-articular tissues, Injuries of the osteoarticular system, Injuries to ligamentsInjuries to the joints, Joint wounds, Stretching of the ligamentous apparatus, Habitual stretching and tearing

Composition and form of release

Gel for external use 2.5% 100 g

ketoprofen 2.5 g

auxiliary substances: carbomer 940; ethanol; Neroli oil; lavender oil; diethanolamine; distilled water

in tubes of aluminum for 30 or 50 grams, in a box of a cardboard 1 tube.

Description of dosage form

A colorless, almost transparent gel with a pleasant smell, non-greasy to the touch.

Characteristic

NSAIDs (non-steroidal anti-inflammatory drugs).

pharmachologic effect

Pharmacological action - anti-inflammatory, analgesic.

The mechanism of action of the drug is associated with inhibition of biosynthesis of PG.

Pharmacodynamics

Fastum gel shows local analgesic, anti-inflammatory, antiexudative action with symptomatic treatment of diseases of joints, tendons, ligaments, muscles, skin, veins, lymphatic vessels and lymph nodes. With articular syndrome, weakening of pain in joints at rest and during movement, reduction of morning stiffness and swelling of the joints.

Pharmacokinetics

With topical application in the form of a gel, it is absorbed extremely slowly and practically does not accumulate in the body. Bioavailability of the gel is about 5%. The dose of 50-150 mg after 5-8 hours creates a level in the plasma of 0.08-0.15 μg / ml.

Indication

Inflammation and pain sensations of different etiology: rheumatism, osteoarthritis of various localization, osteochondrosis, ankylosing spondylitis, gout attack, rheumatoid arthritis and periarthritis; Bursitis, tendonitis, tendosinovitis, synovitis; sciatica, myalgia, radiculitis; bruises, dislocations, stretching of muscles; phlebitis, thrombophlebitis of superficial veins, lymphangitis.

Contraindications

Individual hypersensitivity to ketoprofen, acetylsalicylic acid or other NSAIDs (including in the anamnesis), gastrointestinal diseases in the acute phase, marked violations of kidney and liver function, blood disorders (leukopenia, thrombocytopenia, hemocoagulation disorders), pregnancy, breast feeding, children under 15 years.

pregnancy and lactation

Contraindicated in pregnancy. For the duration of treatment, breastfeeding should be discontinued.

Side effects

Possible allergic reactions from the skin (itching, urticaria) with prolonged use.

Dosing and Administration

On skin, apply a small amount of gel (3-5 cm) a thin layer on the skin above the focus of inflammation and lightly rub 1-2 times a day. The duration of the course of treatment without consulting a doctor should not exceed 14 days.

Precautionary measures

If any side effects occur, discontinue use and consult a doctor.

Avoid getting the gel on the damaged surface of the skin, open wounds, eyes and other mucous membranes.

Before using the drug should consult with a doctor if the liver and / or kidney function, gastrointestinal diseases in history; bronchial asthma, rhinitis, hives, polyps of the nasal mucosa; heart failure.

You should consult your doctor before using the gel while taking other medications.

Store Conditions

In the dark place at a temperature of 15-25 ° C.

Keep out of the reach of children.

Shelf life

5 years.

Do not use after the expiry date printed on the package.